K2P Potassium Channels, Mysterious and Paradoxically Exciting
نویسندگان
چکیده
منابع مشابه
Temperature sensitivity of two-pore (K2P) potassium channels.
At normal body temperature, the two-pore potassium channels TREK-1 (K2P2.1/KCNK2), TREK-2 (K2P10.1/KCNK10), and TRAAK (K2P4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium. Heat dramatically potentiates K2P channel activity and further affects excitation. This review focuses on the current understanding of the physiological role of heat-activated K2P c...
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ژورنال
عنوان ژورنال: Science Signaling
سال: 2011
ISSN: 1945-0877,1937-9145
DOI: 10.1126/scisignal.2002225